The ECS or endocannabinoid system is a messaging system in your body (a series of chemical transmitters and receptors) that modulate just about every physiological function in your body. An under-functioning ECS can lead to Clinical Endocannabinoid Deficiency Syndrome or CEDS.

What is CEDS?

Clinical Endocannabinoid Deficiency Syndrome (CEDS) occurs when your endocannabinoid system is under functioning. This can happen for many reasons, such as lifestyle triggers or genetic factors and can present as many indications.

Anxiety and Depression

Migraines and Headaches

Gastro-intestinal and Metabolism Dysfunction

Nerve Vulnerability and Deterioration

Pain, Inflammation and Fibromyalgia

Repetitive Failed Treatment

Memory and Thinking Issue

Cognition Problems

Insomnia and Sleep Issues

What is the Endocannabinoid System

The endocannabinoid system (ECS):

  • regulates pain and inflammation pathways in your joints and organs
  • affects how you sleep and how you feel (emotions)
  • regulates your appetite and metabolism
  • affects your memory and thinking (cognition)
  • regulates gastro-intestinal / gut function
  • regulates the protection and development of nerves in your body

The ECS is a network of chemical signals and cellular receptors that are densely packed throughout our brains and bodies. CB1 and CB2 are two key cannabinoid receptors that control the levels of activity for the points above. Essentially, these receptors regulate many bodily functions by letting different parts of our body talk to one another. If we are hungry or full, hot or cold, happy or sad our ECS adjusts our body accordingly to meet the needs of our external environment. 

In order for our body to regulate these functions, it naturally produces endocannabinoids, which are structurally similar to the compounds found in the cannabis plant. The first endocannabinoid was discovered in 1992 by our dear friend Dr Raphael Mechoulam. It was named anandamide after the Sanskrit word for bliss. Since then, we have discovered our body makes several endocannabinoids which all have an important role in the normal function of our body. This is a relatively new area of research and we are still discovering new endocannabinoids and the part they play in our physiology.

Today, we have a wealth of research that is indicating some symptoms are the result of our body’s inability to produce an adequate amount of endocannabinoids.

If you're ready to begin your eCS journey

Otherwise, if you have questions feel free to reach out to our clinic team:


03 9117 9000, Australia-wide



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We’re here to support you. Our team are experts on the endocannabinoid system and the treatments used for Clinical Endocannabinoid Deficiency Syndrome.

If you need urgent medical attention, please dial 000 immediately.